Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy (NCT07225686)
A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy and Living With Overweight or Obesity
🩺 Plain-English Summary (8th-Grade Level)
This Phase 3 clinical trial is designed to evaluate the efficacy and safety of maridebart cafraglutide compared to placebo over a 52-week period in adults with obstructive sleep apnea (OSA) who are receiving positive airway pressure (PAP) therapy and are living with overweight or obesity.
Who can join: Review the eligibility criteria below.
Location: Valley Clinical Trials — Northridge, California
Age range: 18 Years to 99 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (61 Sites)
Showing the first 25 of 61 sites.
- Valley Clinical Trials — Northridge, California
- Peninsula Research Associates — Rolling Hills Estates, California
- Teradan Clinical Trials — Brandon, Florida
- Destiny Research Center — Palmetto Bay, Florida
- Clinical Research Center Of Florida — Pompano Beach, Florida
- NeuroTrials Research — Atlanta, Georgia
- Basil Clinical — Laurelton, New York
- Monroe Biomedical Research — Monroe, North Carolina
- CTI Clinical Research Center — Cincinnati, Ohio
- FutureSearch Trials of Neurology — Austin, Texas
- Epic Medical Research - DeSoto — DeSoto, Texas
- Sleep Therapy & Research Center — San Antonio, Texas
- Northwest Clinical Research Center — Bellevue, Washington
- Woolcock Institute of Medical Research — Macquarie Park, New South Wales
- Royal Brisbane and Womens Hospital — Herston, Queensland
- Monash Medical Centre — Clayton, Victoria
- Nucleo de Pesquisa do Rio Grande do Sul — Porto Alegre, Rio Grande do Sul
- Instituto de Pesquisa Clinica de Campinas - Ipecc — Campinas, São Paulo
- CPQuali Pesquisa Clinica Ltda — São Paulo, São Paulo
- Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo Hcfmusp — São Paulo, São Paulo
- Centro Paulista de Investigacao Clinica Cepic — São Paulo,
- CaRe Clinic — Calgary, Alberta
- Aggarwal and Associates Ltd — Brampton, Ontario
- Wharton Medical Clinic — Hamilton, Ontario
- Diex Recherche Trois Rivieres — Trois-Rivières, Quebec
📞 Contact the Study Coordinator
Phone: (866) 572-6436
Email: medinfo@amgen.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.