Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy (NCT07226765)
A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure Therapy and Living With Overweight or Obesity (MARITIME-OSA-2)
🩺 Plain-English Summary (8th-Grade Level)
This Phase 3 clinical trial is designed to evaluate the efficacy and safety of maridebart cafraglutide compared to placebo over a 52-week period in adults with obstructive sleep apnea (OSA) who are not on PAP therapy and are living with overweight or obesity.
Who can join: Review the eligibility criteria below.
Location: Valley Clinical Trials — Northridge, California
Age range: 18 Years to 99 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (57 Sites)
Showing the first 25 of 57 sites.
- Valley Clinical Trials — Northridge, California
- Peninsula Research Associates — Rolling Hills Estates, California
- Teradan Clinical Trials — Brandon, Florida
- Destiny Research Center — Palmetto Bay, Florida
- Clinical Research Center Of Florida — Pompano Beach, Florida
- NeuroTrials Research — Atlanta, Georgia
- Basil Clinical — Laurelton, New York
- Monroe Biomedical Research — Monroe, North Carolina
- CTI Clinical Research Center — Cincinnati, Ohio
- FutureSearch Trials of Neurology — Austin, Texas
- Epic Medical Research - DeSoto — DeSoto, Texas
- Sleep Therapy & Research Center — San Antonio, Texas
- Northwest Clinical Research Center — Bellevue, Washington
- Woolcock Institute of Medical Research — Macquarie Park, New South Wales
- Royal Brisbane and Womens Hospital — Herston, Queensland
- Monash Medical Centre — Clayton, Victoria
- Nucleo de Pesquisa do Rio Grande do Sul — Porto Alegre, Rio Grande do Sul
- Instituto de Pesquisa Clinica de Campinas - Ipecc — Campinas, São Paulo
- CPQuali Pesquisa Clinica Ltda — São Paulo, São Paulo
- Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo Hcfmusp — São Paulo, São Paulo
- Centro Paulista de Investigacao Clinica Cepic — São Paulo,
- CaRe Clinic — Calgary, Alberta
- Aggarwal and Associates Ltd — Brampton, Ontario
- Wharton Medical Clinic — Hamilton, Ontario
- Diex Recherche Trois Rivieres — Trois-Rivières, Quebec
📞 Contact the Study Coordinator
Phone: (866) 572-6436
Email: medinfo@amgen.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Obstructive Sleep Apnea
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- Validation of Sleep Questionnaires in the Down Syndrome Population — Portland, Oregon
- 3D Printer Modified CPAP Mask for Obstructive Sleep Apnea — Boston, Massachusetts
- Breathing Training for Improving Cardiovascular Health in Older Adults With Sleep Apnea — Tucson, Arizona
- Obstructive Sleep Apnea in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation — Memphis, Tennessee
- Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC) — New York, New York
Explore by condition: All Obstructive Sleep Apnea clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.