Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants (NCT07230834)
A Phase 1 Dose-Escalation and Repeated-Dose Study of the Safety and Tolerability of Intravitreal Pozelimab in Participants With Geographic Atrophy
🩺 Plain-English Summary (8th-Grade Level)
This study is researching an experimental drug called pozelimab (called "study drug"). The study is focused on people with a condition where certain parts of the eye's retina stop working over time, which can make it harder to see. This is called geographic atrophy (GA). The aim of the study is to see how safe and tolerable the study drug is when used as an injection in the eye. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood and the fluid in the eye at different times * Whether the body makes antibodies against the study drug (which could make the drug less effective or could lead to side effects)
Who can join: Review the eligibility criteria below.
Location: Colorado Retina Associates — Lakewood, Colorado
Age range: 50 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Colorado Retina Associates — Lakewood, Colorado
- Ophthalmic Consultants of Boston — East Weymouth, Massachusetts
- Austin Retina Associates — Austin, Texas
- Retina Foundation of the Southwest — Dallas, Texas
- Retina Consultants Texas — The Woodlands, Texas
- Arensia Exploratory Medicine at the Research Institute of Clinical Medicine — Tbilisi,
- Emanuelli Research and Development Center — Arecibo,
- ARENSIA Clinics SRL — Bucharest,
- Arensia Exploratory Medicine Clinic at Country Hospital Cluj-Napoca — Cluj-Napoca,
📞 Contact the Study Coordinator
Phone: (844) 734-6643
Email: clinicaltrials@regeneron.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Geographic Atrophy (GA)
Explore by condition: All Geographic Atrophy (GA) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.