🏛️ Verified NIH Record • Updated 2026-08-05
A Study of DII235 in Adults With Elevated Lipoprotein(a) (NCT07235046)
A Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-finding Study to Evaluate Efficacy, Safety, and Tolerability of DII235 in Adults With Elevated Lipoprotein(a)
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Novartis Pharmaceuticals
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study is to determine the safety and efficacy of DII235 in adults with elevated lipoprotein(a).
Who can join: Review the eligibility criteria below.
Location: Parkway Medical Center — Birmingham, Alabama
Age range: 18 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (63 Sites)
Showing the first 25 of 63 sites.
- Parkway Medical Center — Birmingham, Alabama
- Heart Center Research Llc — Huntsville, Alabama
- Cardiology and Medicine Clinic PA — Little Rock, Arkansas
- National Heart Institute — Beverly Hills, California
- Alliance Clinical — Canoga Park, California
- Excel Medical Clinical Trials LLC — Boca Raton, Florida
- Zenith Clinical Research — Hollywood, Florida
- Jacksonville Center for Clinical Research — Jacksonville, Florida
- Flourish Res Acq LLC North Miami — Miami, Florida
- Inpatient Research Clinical LLC — Miami Lakes, Florida
- Ocala Cardiovascular Research — Ocala, Florida
- SEC Clinical Research — Pensacola, Florida
- Cardiology Partners Clinical Research Institute — Wellington, Florida
- Atlanta Heart Specialists LLC — Tucker, Georgia
- AMR Chicago — Niles, Illinois
- CV Ins of the South — Lafayette, Louisiana
- Monroe Research Llc — West Monroe, Louisiana
- Metropolitan Cardiovascular Consultants Llc — Beltsville, Maryland
- Anderson Medical Research — Ft. Washington, Maryland
- Capitol Cardiology Associates — Lanham, Maryland
- AA Medical Research Center — Flint, Michigan
- Trinity Health Michigan Heart — Ypsilanti, Michigan
- Cardiology Associates of North MS — Tupelo, Mississippi
- AB Clinical Trials — Las Vegas, Nevada
- K and R Research LLC — Marion, Ohio
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Lipoprotein Disorder
- Extreme Lipids Repository — Dallas, Texas
- Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a) — Los Angeles, California
Explore by condition: All Lipoprotein Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.