Psilocybin to Treat Depression in Spinal Cord Injury (NCT07251491)
Safety, Tolerability, Outcomes of Psilocybin for Depression (STOP Depression) in Veterans With Spinal Cord Injury
🩺 Plain-English Summary (8th-Grade Level)
The main goal of this study is to determine if psilocybin is safe for use in people with SCI. The study will measure how people with SCI respond to three psilocybin doses: low (5mg), medium (10mg), and high (25mg). The main question the study aims to answer is: does psilocybin increase the number and severity of adverse (bad) events reported by people with SCI? These may include pain, muscle spasms, symptoms of depression, and symptoms of low or high blood pressure. The investigators will also measure how well people with SCI tolerate the psychedelic experience, and compare responses between the low (5mg), medium (10mg), and high (25mg) doses. Participants will: * Agree to be enrolled in the study for up to 13 months. * Agree to complete the seven (7) visits that are included in the psilocybin-assisted therapy. * Agree to complete follow-up study visits, including in-person visits to the James J Peters VA Medical Center, located in the Bronx, New York and remote visits. * Agree to keep a log of how they are feeling and any change in the frequency or severity of adverse events.
Who can join: Review the eligibility criteria below.
Location: James J. Peters Department of Veterans Affairs Medical Center — The Bronx, New York
Age range: 22 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- James J. Peters Department of Veterans Affairs Medical Center — The Bronx, New York
📞 Contact the Study Coordinator
Phone: (718) 584-9000
Email: Thomas.Sutor@mountsinai.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Spinal Cord Injury
- AIH-induced Walking Recovery After Subacute SCI — Atlanta, Georgia
- C-Brace II Spinal Cord Injury — Chicago, Illinois
- Autonomic Effects of Stimulation in SCI — The Bronx, New York
- Time Restricted Eating to Mitigate Obesity in Veterans With Spinal Cord Injury — Syracuse, New York
- Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury — Cleveland, Ohio
- Electrical Stimulation for Continence After Spinal Cord Injury — Palo Alto, California
Explore by condition: All Spinal Cord Injury clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.