Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC) (NCT07252232)
RASolute 304: A Phase 3 Multicenter, Open-label, Randomized, 2-Arm Study of Adjuvant Daraxonrasib Versus Standard of Care Observation Following Completion of Neoadjuvant and/or Adjuvant Chemotherapy in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic โ Phoenix, Arizona
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (66 Sites)
Showing the first 25 of 66 sites.
- Mayo Clinic โ Phoenix, Arizona
- UC San Diego Moores Cancer Center โ La Jolla, California
- Cedars-Sinai Cancer at Cedars-Sinai Medical Center โ Los Angeles, California
- University of California, Los Angeles โ Los Angeles, California
- Stanford Cancer Institute โ Palo Alto, California
- University of California, San Francisco โ San Francisco, California
- Rocky Mountain Cancer Centers, LLP โ Lakewood, Colorado
- Hartford Healthcare โ Hartford, Connecticut
- Mayo Clinic โ Jacksonville, Florida
- University of Miami Hospital and Clinics, Sylvester Comprehensive Cancer Center โ Miami, Florida
- Florida Cancer Specialists โ St. Petersburg, Florida
- Winship Cancer Institute, Emory University โ Atlanta, Georgia
- Community Health Network โ Indianapolis, Indiana
- University of Kansas Medical Center Research Institute, Inc. โ Lawrence, Kansas
- Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins & Sibley Memorial Hospital โ Baltimore, Maryland
- Massachusetts General Hospital โ Boston, Massachusetts
- Dana Farber Cancer Institute (DFCI) โ Boston, Massachusetts
- Mayo Clinic Cancer Center โ Rochester, Minnesota
- Saint Luke's Cancer Institute โ Kansas City, Missouri
- University of Nebraska Medical Center โ Omaha, Nebraska
- Comprehensive Cancer Centers of Nevada โ Las Vegas, Nevada
- Laura and Issac Perlmutter Cancer Center at NYU Langone-Ambulatory Care Center โ New York, New York
- Columbia University Medical Center โ New York, New York
- Memorial Sloan Kettering Cancer Center โ New York, New York
- University of Rochester Medical Center โ Rochester, New York
๐ Contact the Study Coordinator
Phone: (480) 342-4800
Email: bekaii-saab.tanios@mayo.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas โ Baltimore, Maryland
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๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.