A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis (NCT07258849)
A Phase 1, Multicenter, Randomized, Placebo-Controlled, Investigator- and Participant-Blinded, Single- and Multiple-Ascending Dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of LY4213663 in Healthy Participants, and Two Open-Label, Multiple-Dose Evaluations of LY4213663 in Patients With Rheumatoid Arthritis.
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate how well LY4213663 is tolerated and what side effects may occur in healthy participants and participants with rheumatoid arthritis (RA). The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body. The study will last approximately 33 weeks excluding screening.
Who can join: Review the eligibility criteria below.
Location: Pinnacle Research Group, LLC — Anniston, Alabama
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (10 Sites)
- Pinnacle Research Group, LLC — Anniston, Alabama
- Arizona Research Center — Phoenix, Arizona
- Clinical Research of West Florida, Inc. (Clearwater) — Clearwater, Florida
- GNP Research at Mark Jaffe, MD — Cooper City, Florida
- Fortrea Clinical Research Unit — Daytona Beach, Florida
- AGA Clinical Trials — Hialeah, Florida
- Advanced Pharma CR, LLC — Miami, Florida
- Floridian Clinical Research — Miami Lakes, Florida
- Oasis Clinical Research — Las Vegas, Nevada
- Universitätsklinikum Charité — Berlin,
📞 Contact the Study Coordinator
Phone: (317) 615-4559
Email: LillyTrials@Lilly.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Rheumatoid Arthritis (RA)
- BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease — Boston, Massachusetts
- Acceptability of a Nurse-led Telehealth Remote Self-monitoring Model of Care in Patients With Rheumatoid Arthritis — Montreal, Quebec
- A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic — San Francisco, California
- Probiotics in Adults With Rheumatoid Arthritis — Chicago, Illinois
- At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study] — Glendale, Arizona
Explore by condition: All Rheumatoid Arthritis (RA) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.