Phentermine's Impact on Treatment in Teens (NCT07282340)
Phentermine's Impact on Treatment in Teens (PhITT): A Randomized Placebo-Controlled Trial of Phentermine for Adolescents With Obesity
🩺 Plain-English Summary (8th-Grade Level)
PhITT is a Phase IIb, multicenter, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of phentermine (16 mg daily) in adolescents aged 12 to \<18 years with obesity. Conducted across approximately 10 sites within the IDeA States Pediatric Clinical Trials Network (ISPCTN), the study aims to enroll up to 240 participants and then randomize up to 198 who meet eligibility criteria, randomized in a 2:1 ratio to phentermine or placebo over a 52-week treatment period, followed by a 2-week withdrawal assessment.
Who can join: Review the eligibility criteria below.
Location: Pennington Biomedical Research Center — Baton Rouge, Louisiana
Age range: 12 Years to 17 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (6 Sites)
- Pennington Biomedical Research Center — Baton Rouge, Louisiana
- Children's Mercy Hospital — Kansas City, Missouri
- Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire
- University of New Mexico Health Sciences Center — Albuquerque, New Mexico
- The University of Oklahoma Health Sciences Children's Hospital — Oklahoma City, Oklahoma
- Prisma Health-Midlands Children's Hospital — Columbia, South Carolina
📞 Contact the Study Coordinator
Phone: (402) 559-4815
Email: aubrey.vanstory@unmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.