๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-20

A Study of Buntanetap in Participants With PD (NCT07284784)

An Open-label Clinical Trial Investigating the Long-term Safety of Buntanetap in Treating Participants With Parkinson's Disease

๐ŸŸข Recruiting Phase2 / Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Annovis Bio Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study will examine the long-term safety of buntanetap in participants with PD. This will be a 36-month open-label safety study. This study will be conducted with two cohorts. Cohort 1 will enroll via invitation only for PD participants who have previously participated in buntanetap clinical trials. Cohort 2 will be for PD participants who are receiving deep brain stimulation (DBS) treatment. Qualified participants will receive buntanetap 30mg QD after a screening period of up to 42 days.

Who can join: Review the eligibility criteria below.

Location: University of Alabama at Birmingham โ€” Birmingham, Alabama

Age range: 40 Years to 85 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (27 Sites)

Showing the first 25 of 27 sites.

  • University of Alabama at Birmingham โ€” Birmingham, Alabama
  • Banner Sun Health Research Institute - Cleo Roberts Center for Clinical Research โ€” Sun City, Arizona
  • Parkinson's & Movement Disorder Institute (PMDI) - Orange County Office โ€” Fountain Valley, California
  • Cenexel Rocky Mountain Clinical Research โ€” Englewood, Colorado
  • New England Institute for Clinical Research (Ki Health Partners) โ€” Stamford, Connecticut
  • First Choice Neurology - Aventura Neurologic Associates โ€” Aventura, Florida
  • Arrow Clinical Trials โ€” Daytona Beach, Florida
  • Accel Clinical Sites-Georgia LLC dba Accel Research Sites-Lake Oconee CRU โ€” DeLand, Florida
  • Renstar Medical Research โ€” Ocala, Florida
  • University of South Florida (USF) - University of South Florida College of Medicine - Parkinson's Di โ€” Tampa, Florida
  • Conquest Research โ€” Winter Park, Florida
  • iResearch Atlanta โ€” Decatur, Georgia
  • Josephson Wallack Munshower Neurology, P.C. โ€” Indianapolis, Indiana
  • University of Kansas Medical Center (KUMC) - School of Medicine - Parkinson's Disease and Movement D โ€” Kansas City, Kansas
  • Quest Research Institute โ€” Farmington Hills, Michigan
  • Mount Sinai Hospital โ€” New York, New York
  • Duke Department of Neurosurgery โ€” Durham, North Carolina
  • The Ohio State University Wexner Medical Center โ€” Columbus, Ohio
  • The Movement Disorder Clinic of Oklahoma โ€” Tulsa, Oklahoma
  • Abington Neurology โ€” Willow Grove, Pennsylvania
  • Medical University of South Carolina (MUSC) - The Murray Center for Research on Parkinson's Disease โ€” Charleston, South Carolina
  • Neurology Clinic, P.C. โ€” Cordova, Tennessee
  • Veracity Neuroscience LLC โ€” Memphis, Tennessee
  • Central Texas Neurology โ€” Round Rock, Texas
  • University of Virginia Health System (UVAHS) - Adult Neurology Clinic โ€” Charlottesville, Virginia

๐Ÿ“ž Contact the Study Coordinator

Phone: (484) 875-3192

Email: maccallum@annovisbio.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—