๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-04

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer (NCT07284849)

A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Incyte Corporation

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer.

Who can join: Review the eligibility criteria below.

Location: Mitchell Cancer Institute โ€” Mobile, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (254 Sites)

Showing the first 25 of 254 sites.

  • Mitchell Cancer Institute โ€” Mobile, Alabama
  • The University of Arizona Cancer Center โ€” Tucson, Arizona
  • Roche Tissue Diagnostics, Companion Diagnostics โ€” Tucson, Arizona
  • Memorial Care Orange Coast Medical Center โ€” Fountain Valley, California
  • Providence Medical Foundation โ€” Fullerton, California
  • Cancer & Blood Research Center โ€” Los Alamitos, California
  • University of California Los Angeles Health โ€” Los Angeles, California
  • Sarah Cannon Research Institute Scri Oncology Partners โ€” Aurora, Colorado
  • Hartford Hospital โ€” Hartford, Connecticut
  • George Washington University โ€” Washington D.C., District of Columbia
  • Florida Oncology & Hematology โ€” Fort Myers, Florida
  • University of Florida Health โ€” Gainesville, Florida
  • Sylvester Comprehensive Cancer Center โ€” Miami, Florida
  • Advent Health โ€” Orlando, Florida
  • Orlando Health Cancer Institute Downtown Orlando โ€” Orlando, Florida
  • Ascension Sacred Heart Pensacola โ€” Pensacola, Florida
  • Tampa General Hospital-Cancer Institute โ€” Tampa, Florida
  • Piedmont Cancer Institute โ€” Locust Grove, Georgia
  • University of Hawaii Cancer Center โ€” Honolulu, Hawaii
  • St Lukes Mountain States Tumor Institute Msti Boise โ€” Boise, Idaho
  • Sih Cancer Institute โ€” Carterville, Illinois
  • University of Illinois Cancer Center โ€” Chicago, Illinois
  • Endeavor Health โ€” Evanston, Illinois
  • Springfield Clinic โ€” Springfield, Illinois
  • Community Health Network, Inc. โ€” Indianapolis, Indiana

๐Ÿ“ž Contact the Study Coordinator

Phone: (855) 463-3463

Email: medinfo@incyte.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—