๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-17

A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206) (NCT07291076)

ROSETTA HCC-206: An Open-Label, Multi-Center, Randomized Phase 1/2 Study of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC)

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Bristol-Myers Squibb

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the safety and tolerability of Pumitamig alone or in combination with Ipilimumab in participants with first-line advanced or unresectable Hepatocellular Carcinoma (HCC)

Who can join: Review the eligibility criteria below.

Location: Local Institution - 0137 โ€” Duarte, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (67 Sites)

Showing the first 25 of 67 sites.

  • Local Institution - 0137 โ€” Duarte, California
  • Local Institution - 0070 โ€” Los Angeles, California
  • Local Institution - 0107 โ€” Chicago, Illinois
  • Local Institution - 0134 โ€” Detroit, Michigan
  • John Theurer Cancer Center at Hackensack University Medical Center โ€” Hackensack, New Jersey
  • Local Institution - 0100 โ€” Mineola, New York
  • Providence Portland Medical Center โ€” Portland, Oregon
  • Providence St. Vincent Medical Center โ€” Portland, Oregon
  • Tennessee Oncology โ€” Nashville, Tennessee
  • Vanderbilt University Medical Center โ€” Nashville, Tennessee
  • Local Institution - 0083 โ€” Seattle, Washington
  • Royal Prince Alfred Hospital โ€” Camperdown, New South Wales
  • Local Institution - 0033 โ€” Westmead, New South Wales
  • Sunshine Coast University Hospital โ€” Birtinya, Queensland
  • The Royal Melbourne Hospital โ€” Parkville, Victoria
  • Bradfordhill โ€” Santiago, Santiago Metropolitan
  • Pontifica Universidad Catolica De Chile โ€” Santiago Region Metropolitana, Santiago Metropolitan
  • Local Institution - 0122 โ€” Hefei, Anhui
  • Local Institution - 0114 โ€” Beijing, Beijing Municipality
  • Local Institution - 0125 โ€” Chongqing, Chongqing Municipality
  • Local Institution - 0116 โ€” Fuzhou, Fujian
  • Local Institution - 0075 โ€” Guangzhou, Guangdong
  • Local Institution - 0129 โ€” Nanning, Guangxi
  • Local Institution - 0130 โ€” Harbin, Heilongjiang
  • Local Institution - 0128 โ€” Nanyang, Henan

๐Ÿ“ž Contact the Study Coordinator

Phone: (855) 907-3286

Email: Clinical.Trials@bms.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—