PREcision MEDicine In Achalasia (PREMEDIA) - Cohort (NCT07293689)
PREcision MEDicine In Achalasia - A Multicenter Randomized Non-Inferiority Clinical Trial of Short Tailored POEM vs. Standard POEM for Non-Spastic Achalasia and A Multicenter Prospective Cohort Study of Long Tailored POEM for Spastic Esophageal Motility Disorders
🩺 Plain-English Summary (8th-Grade Level)
The goal of this observational study is to learn about how the doctor decides how long to cut t the esophageal muscle during Per-Oral Endoscopic Myotomy (POEM) in patients with difficulty swallowing due to certain conditions. The main question it aims to answer is: does pre-POEM testing help the physician choose how long to cut the muscle. Participants will allow researchers to access their standard of care information in their medical record, complete questionnaires at up to 6 times over a 2-year period.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic Arizona — Scottsdale, Arizona
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (16 Sites)
- Mayo Clinic Arizona — Scottsdale, Arizona
- University of California San Diego — La Jolla, California
- University of Colorado Denver — Denver, Colorado
- University of Florida — Gainesville, Florida
- Adventist Health System/Sunbelt, Inc — Orlando, Florida
- Emory University — Atlanta, Georgia
- Northwestern University — Chicago, Illinois
- Johns Hopkins University — Baltimore, Maryland
- Massachusetts General Hospital — Boston, Massachusetts
- Washington University — St Louis, Missouri
- Weill Cornell Medical College — New York, New York
- Atrium Health/Wake Forest — Charlotte, North Carolina
- Case Western Reserve University — Cleveland, Ohio
- MetroHealth Medical Center — Cleveland, Ohio
- Vanderbilt University Medical Center — Nashville, Tennessee
- Baylor Scott & White Health — Dallas, Texas
📞 Contact the Study Coordinator
Phone: (312) 908-1723
Email: premedia.dcc@northwestern.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Type III Achalasia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.