Overcoming Barriers to Uptake of Cascade Screening (NCT07304063)
Let's Talk: Overcoming Barriers to Uptake of Cascade Screening Through a Stakeholder-informed Online Intervention
🩺 Plain-English Summary (8th-Grade Level)
Lynch syndrome is a genetic condition that increases cancer risk. The public health impact of genetic testing for disease prevention hinges on cascade screening, which is the systematic identification and testing of blood relatives after a family member has been diagnosed with a genetic condition. Despite its importance in disease prevention, only half of first-degree relatives of individuals with Lynch syndrome undergo cascade screening. To address this gap, the study will pilot test an online version of Let's Talk, a novel intervention designed to support and promote cascade screening. This intervention tool is designed to support and encourage more family members to get screened. The purpose of this study aim is to assess the feasibility of the online Let's Talk tool in clinical use by examining implementation and effectiveness outcomes related to the use of the planning tool across three clinics at a large academic-affiliated medical center with patients (n=15) seen by one of five genetic counselors (n=5).
Who can join: Review the eligibility criteria below.
Location: University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
Age range: 18 Years
🧪 Interventions in This Study
- Let's Talk Genetics Providers (BEHAVIORAL)
- Let's Talk Patients (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
📞 Contact the Study Coordinator
Phone: (919) 984-0000
Email: Rebecca_Bosch@med.unc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Lynch Syndrome
- Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes — New York, New York
- Multi-Organ Screening Recommendations in Patients With Lynch Syndrome — Basking Ridge, New Jersey
- Lynch Syndrome X-Talk of Enteral Mucosa With Immune System — Monrovia, California
- A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule — Boston, Massachusetts
- Lynch Syndrome Integrative Epidemiology and Genetics — Aurora, Colorado
Explore by condition: All Lynch Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.