Human Laboratory Study of Apremilast for Alcohol Use Disorder (NCT07325266)
🩺 Plain-English Summary (8th-Grade Level)
Primary: The primary objective of this study is to compare the efficacy of two different maintenance doses of apremilast (tablets) in reducing alcohol craving among subjects with moderate to severe alcohol use disorder (AUD) after two weeks of daily dosing. Secondary: Secondary objectives include evaluation of two different maintenance doses of apremilast compared with matched placebo on other measures of self-reported alcohol consumption, alcohol craving, alcohol-related negative consequences, AUD symptoms, pain, sleep disturbances, depression, anxiety, quality of life, cigarette smoking, other nicotine use, cannabis use, retention in the study, and safety.
Who can join: Review the eligibility criteria below.
Location: University of California — Los Angeles, California
Age range: 21 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- University of California — Los Angeles, California
- University of Colorado — Aurora, Colorado
- University of Virginia — Charlottesville, Virginia
📞 Contact the Study Coordinator
Phone: (301) 443-4225
Email: mryan1@nih.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Alcohol Use Disorder
- Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on Alcoholism — Portland, Oregon
- Alcoholic Liver Disease and the Gut Microbiome — Los Angeles, California
- Telehealth Treatment for Alcohol Use Disorder — Stanford, California
- Remote Alcohol Monitoring to Facilitate Abstinence From Alcohol: Exp 1 — Lexington, Kentucky
- Psilocybin-Assisted vs Ketamine-Assisted Psychotherapy for Alcohol Use Disorder — Iowa City, Iowa
- rTMS in Older Adults With MCI and AUD — Charleston, South Carolina
Explore by condition: All Alcohol Use Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.