Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.2 (NCT07339072)
Temporal Interference Methods for Non-invasive Deep Brain Stimulation
π©Ί Plain-English Summary (8th-Grade Level)
In its totality, this grant aims to develop a line of research using temporal interference (TI) electrical neurostimulation technology to understand the causal role of deep brain structures in cognition. In the short term, the investigators aim to validate and characterize the effects of TI on brain activity as measured by fMRI and demonstrate its ability to focally stimulate deep brain regions without affecting overlying cortex. In the longer term, investigators aim to use these data to resolve longstanding debates about the function of deeper brain regions and lay the foundation for future clinical applications of TI for treating addiction, Obsessive-Compulsive Disorder (OCD), Parkinson's disease, and other disorders involving deep brain dysfunction. The grant supports 2 distinct aims, each of which will be evaluated through a series of independent studies.
Who can join: Review the eligibility criteria below.
Location: Indiana University Bloomington, Imaging Research Facility β Bloomington, Indiana
Age range: 18 Years to 50 Years
π§ͺ Interventions in This Study
- Temporal Interference (TI) Electrical Stimulation - NAcc 5 Hz TI Active (DEVICE)
- Temporal Interference (TI) Electrical Stimulation - NAcc 5 Hz TI Sham (DEVICE)
- Temporal Interference (TI) Electrical Stimulation - NAcc 10 Hz TI Active (DEVICE)
- Temporal Interference (TI) Electrical Stimulation - NAcc 10 Hz TI Sham (DEVICE)
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (1 Sites)
- Indiana University Bloomington, Imaging Research Facility β Bloomington, Indiana
π Contact the Study Coordinator
Phone: (812) 855-9282
Email: jwmbrown@iu.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Healthy Volunteers
- Pharmacokinetics and Tolerability of Subcutaneous Dupilumab Coformulated With Berahyaluronidase Alfa and Dupilumab Without Berahyaluronidase Alfa in Healthy Participants β Hialeah, Florida
- A First-in-human, 3-part Study of MRT-8102 in Healthy Participants and Participants at Cardiovascular Risk With Elevated CRP β Miami, Florida
- A Phase 1 Study to Assess the Effect of Itraconazole on ABBV-722 in Healthy Adult Participants β Grayslake, Illinois
- Flavanol-rich Cocoa on Digestive and Cerebrovascular Health in the Colombian Adults β MedellΓn, Antioquia
- ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study β Bethesda, Maryland
- A First-in-Human Phase 1 Single-Ascending Dose Study of ABCL575 in Healthy Participants β Mount Royal, Quebec
Explore by condition: All Healthy Volunteers clinical trials
π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.