AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight (NCT07339423)
Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Obesity (AMAZE 1)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.
Who can join: Review the eligibility criteria below.
Location: South Broward Research LLC — Miramar, Florida
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (72 Sites)
Showing the first 25 of 72 sites.
- South Broward Research LLC — Miramar, Florida
- Clinical Neuroscience Solution — Orlando, Florida
- Hope Clin Res & Wellness — Conyers, Georgia
- Endeavor Health — Skokie, Illinois
- Midwest Inst For Clin Res — Indianapolis, Indiana
- StudyMetrix Research LLC — City of Saint Peters, Missouri
- New York Gastroenterology Associates — New York, New York
- UNC Eastowne Medical Office — Chapel Hill, North Carolina
- PharmQuest Life Sciences LLC — Greensboro, North Carolina
- Accellacare and KDCILM, LLC — Wilmington, North Carolina
- UPA Ctr Weight and Eating Dis — Philadelphia, Pennsylvania
- Clinical Res Collaborative — Cumberland, Rhode Island
- Medical Uni of SC Charleston — Charleston, South Carolina
- Coastal Carolina Research Ctr — North Charleston, South Carolina
- Hillcrest Clinical Research — Simpsonville, South Carolina
- Amarillo Medical Specialists — Amarillo, Texas
- Velocity Clinical Res-Dallas — Dallas, Texas
- Care United Research, LLC — Forney, Texas
- Washington Cntr Weight Mgmt — Arlington, Virginia
- Health Res of Hampton Roads — Newport News, Virginia
- Selma Medical Associates — Winchester, Virginia
- Rainier Clin Res Ctr Inc — Renton, Washington
- Fundación CESIM — Santa Rosa, La Pampa Province
- Centro Medico Dra. Laura Maffei e Investigacion Clínica Apli — Buenos Aires,
- Instituto de Investigaciones Clínicas Córdoba — Córdoba,
📞 Contact the Study Coordinator
Phone: (866) 867-7178
Email: clinicaltrials@novonordisk.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.