The Rhinovirus Hospitalization and Investigation of Nasal-airway Omics (RHINO) Study (NCT07342582)
Identifying the Burden of Hospitalization Due to Rhinovirus (RV) in Children and Mechanisms of Pathogenesis Using Airway Molecular Profiling
🩺 Plain-English Summary (8th-Grade Level)
The goal of this study is to determine the burden of Rhinoviruses (RVs) as a cause of acute, severe, respiratory illnesses leading to hospitalization. A community cohort of 120 children between 12 and 36 months of age will be enrolled in the first year of the study and followed (when well and sick) for 36 months to identify the circulating RVs and provide samples to establish a host nasal transcriptome differentiating clinical from subclinical RV infections. A hospitalized cohort of 450 infants and children will be enrolled during years 1 through 3 of the study and followed for the duration of their hospitalization to investigate the findings of the community cohort. An additional 100 healthy children aged 5-17.5 years will be enrolled for age-match comparison with the older hospitalized cohort.
Who can join: Review the eligibility criteria below.
Location: University of Wisconsin — Madison, Wisconsin
Age range: Not specified to 17 Years
🧪 Interventions in This Study
- Nasal Swab Healthy Surveillance (DIAGNOSTIC_TEST)
- Nasal Swab Sick Samples (DIAGNOSTIC_TEST)
- Nasal Swab Hospitalized Cohort (DIAGNOSTIC_TEST)
- Sick Follow-up Survey (OTHER)
- Older Cohort Control Group (OTHER)
- Procedural Comfort or Care (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Wisconsin — Madison, Wisconsin
📞 Contact the Study Coordinator
Phone: (608) 228-4940
Email: reserachnurses@pediatrics.wisc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Rhinovirus clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.