Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder. (NCT07347405)
A Randomized Double-masked Dose-controlled Trial to Assess the Tolerability, Safety, Subjective Experience, and Efficacy of Repeated Administration of Three Different Doses of Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.
🩺 Plain-English Summary (8th-Grade Level)
The study tries to improve our treatments for people who have obsessive-compulsive disorder (OCD) by testing psilocybin, a mind altering drug that changes activity in brain areas involved in OCD. 30 patients with moderate or more severe OCD who are not taking mind altering medications or street drugs will participate in a 12 week study. Participants will be assigned (by luck of the draw) to take a low, medium, or high dose whole psilocybin mushroom contained in three chocolate pieces, prepared for this study by the Scottsdale Research Institute.
Who can join: Review the eligibility criteria below.
Location: The Clinical and Translational Sciences Research Center — Tucson, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- The Clinical and Translational Sciences Research Center — Tucson, Arizona
📞 Contact the Study Coordinator
Phone: (520) 626-8000
Email: OCD@psychiatry.arizona.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Obsessive-Compulsive Disorder
- Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD — Toronto, Ontario
- Effects of Psilocybin in Obsessive Compulsive Disorder — Baltimore, Maryland
- Development of Adaptive Deep Brain Stimulation for OCD — Pittsburgh, Pennsylvania
- Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder — Pittsburgh, Pennsylvania
- Personalized DBS for OCD Guided by Stereoencephalography Mapping — San Francisco, California
- Brain Recordings in Patients Undergoing Deep Brain Stimulation (DBS) for Severe Obsessive-Compulsive Disorder (OCD) — Houston, Texas
Explore by condition: All Obsessive-Compulsive Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.