πŸ›οΈ Verified NIH Record β€’ Updated 2026-06-08

A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight (NCT07357415)

A Phase 3b Study to Investigate the Efficacy and Safety of Different Retatrutide Dose Escalation Schemes in Participants Without Type 2 Diabetes Who Have Obesity or Overweight: A Randomized, Controlled, Double-Blind Trial

πŸ”΅ Active, Not Recruiting Phase3 πŸ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to investigate the efficacy and safety of different retatrutide dose escalation schemes in participants without type 2 diabetes who have obesity or overweight. Participation in the study will last about 113 weeks.

Who can join: Review the eligibility criteria below.

Location: Arizona Research Center β€” Phoenix, Arizona

Age range: 18 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (35 Sites)

Showing the first 25 of 35 sites.

  • Arizona Research Center β€” Phoenix, Arizona
  • Care Access - Huntington Beach β€” Huntington Beach, California
  • Los Angeles Institute for Metabolic Research β€” Los Angeles, California
  • New Horizon Research Center β€” Miami, Florida
  • Encore Medical Research - Weston β€” Weston, Florida
  • Pacific Diabetes & Endocrine Center β€” Honolulu, Hawaii
  • Monroe Biomedical Research - Louisville β€” Louisville, Kentucky
  • Brigham and Women's Hospital Diabetes Program β€” Boston, Massachusetts
  • Great Lakes Research Group, Inc. β€” Bay City, Michigan
  • NYC Research INC β€” Long Island City, New York
  • Weill Cornell Medical College β€” New York, New York
  • Care Access - Raleigh β€” Raleigh, North Carolina
  • New Phase Research and Development β€” Knoxville, Tennessee
  • Velocity Clinical Research, Dallas β€” Dallas, Texas
  • Cedar Health Research - Texas Native Health β€” Dallas, Texas
  • Cedar Health Research β€” Dallas, Texas
  • Cedar Health Research - Fort Worth β€” Fort Worth, Texas
  • Advanced Research Institute β€” Ogden, Utah
  • Dominion Medical Associates, Inc. β€” Richmond, Virginia
  • CAMC Institute for Academic Medicine β€” Charleston, West Virginia
  • Cicemo Srl β€” Buenos Aires,
  • CARDIAMET Investigaciones MΓ©dicas β€” Buenos Aires,
  • Stat Research S.A. β€” Buenos Aires,
  • Centro de Investigaciones MetabΓ³licas (CINME) β€” Buenos Aires,
  • Centro MΓ©dico Viamonte β€” Buenos Aires,

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Obesity clinical trials

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—