A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight (NCT07369011)
A Master Protocol for Phase 3 Randomized, Double-Blind, Placebo-Controlled Studies to Investigate the Efficacy and Safety of Once Weekly Eloralintide in Adult Participants With Moderate to Severe Obstructive Sleep Apnea, and Obesity or Overweight
🩺 Plain-English Summary (8th-Grade Level)
The purpose of the studies is to evaluate the efficacy and safety of eloralintide in participants with moderate-to-severe obstructive sleep apnea and obesity or overweight. YDAO is a master protocol designed to support two independent studies: YSA1 and YSA2. Study YSA1 will include participants who are unable or unwilling to use Positive Airway Pressure (PAP) therapy and study YSA2 will include participants who are on PAP therapy for at least 3 months at time of screening and plan to continue PAP therapy during the study. Participants will be assigned to the Intervention-Specific Appendix (ISA) that reflects their current PAP usage. Participation in the study will last about 76 weeks.
Who can join: Review the eligibility criteria below.
Location: Cullman Clinical Trials — Cullman, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (115 Sites)
Showing the first 25 of 115 sites.
- Cullman Clinical Trials — Cullman, Alabama
- Ark Clinical Research — Long Beach, California
- Collaborative Neuroscience Research, LLC — Los Alamitos, California
- Artemis Institute for Clinical Research — Riverside, California
- Care Access - Aurora — Aurora, Colorado
- Flourish Research - Miami, LLC — Miami, Florida
- PharmaDev Clinical Research Institute, LLC — Miami, Florida
- Emerald Coast Neurology - Airport Boulevard — Pensacola, Florida
- Teak Research Consults — Lawrenceville, Georgia
- EBGS Clinical Research Center — Snellville, Georgia
- Care Access - Shreveport 2 — Shreveport, Louisiana
- Flourish Research - Bowie — Bowie, Maryland
- Revive Research Institute, Inc. — Southfield, Michigan
- Headlands Research-Twin Cities — Maplewood, Minnesota
- Clayton Sleep Institute - St. Louis - Tesson Ferry Road — St Louis, Missouri
- Palm Research Center Tenaya — Las Vegas, Nevada
- The Sleep Spot - Maimonides — Albuquerque, New Mexico
- Rochester Clinical Research - Buffalo — Buffalo, New York
- CTI Clinical Research Center — Cincinnati, Ohio
- Bogan Sleep Consultants — Columbia, South Carolina
- FutureSearch Trials of Neurology — Austin, Texas
- Sleep Therapy Research Center — San Antonio, Texas
- Consano Clinical Research, LLC — Shavano Park, Texas
- Nightingale Research — Adelaide,
- Flinders University — Bedford Park,
📞 Contact the Study Coordinator
Phone: (317) 615-4559
Email: LillyTrials@Lilly.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Sleep Apnea, Obstructive
- Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA. — Colorado Springs, Colorado
- Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics — Baltimore, Maryland
- Long-term Evaluation of a Nasopharyngeal Airway — Ann Arbor, Michigan
- The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention — Charleston, South Carolina
- The IPAD Cohort Study: Insomnia and Positive Airway Pressure Adherence in Children and Adolescents — Vancouver, British Columbia
Explore by condition: All Sleep Apnea, Obstructive clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.