ALDH2 Genetic Testing in East Asian Community (NCT07392775)
A Community-Based Approach for ALDH2 Genetic Testing in East Asian Americans
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to learn whether education plus genetic testing for ALDH2\*2 and ADH1B\*2 is feasible and acceptable and whether it influences modifiable health behaviors in East Asian American adults who experience alcohol flushing when they drink alcohol or have a family history of flushing. The main questions it aims to answer are: 1. Is providing education plus ALDH2\*2/ADH1B\*2 genetic testing feasible and acceptable in a clinical care context? 2. Does receiving genetic testing results plus education lead to changes in modifiable health behaviors compared with education alone? Researchers will compare education plus genetic testing (intervention arm) to education only (control arm) to see if adding genetic testing improves feasibility/acceptability and supports health behavior change. Participants will: 1. Complete an education module about alcohol flushing and ALDH2/ADH1B 2. Be randomized to either: (A) Receive genetic testing for ALDH2\*2 and ADH1B\*2 with results disclosure, or (B) Receive education only. 3. Complete follow-up measures about feasibility, acceptability, and modifiable health behaviors
Who can join: Review the eligibility criteria below.
Location: Northwestern University Feinberg School of Medicine — Chicago, Illinois
Age range: 18 Years
🧪 Interventions in This Study
- Genetic Test Results Return (BEHAVIORAL)
- Alcohol Flushing Education (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Northwestern University Feinberg School of Medicine — Chicago, Illinois
📞 Contact the Study Coordinator
Phone: (206) 453-8538
Email: fiona.seung@northwestern.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Healthy Adult
- The Effects of Finger Extensor Training on Climbing Performance Compared With Traditional Flexor Training — Portland, Oregon
- Effect of Monosodium Glutamate on Microbiome-Derived Imidazole Propionate Production in Healthy Volunteers — Chicago, Illinois
- Finding Immune Nascent Type 1 Diabetes — Indianapolis, Indiana
- Ivabradine for Heart Rate Reduction During Exercise in Healthy Adults — Vancouver, British Columbia
- Comparison Between Eccentric Hamstring Training and Sprint-Specific Training — Madison, Wisconsin
Explore by condition: All Healthy Adult clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.