🏛️ Verified NIH Record • Updated 2026-05-26

Shape-sensing Versus Electromagnetic Robotic Bronchoscopy for Evaluation of PulmoNary LEsions (NCT07411989)

Shape-sensing Versus Electromagnetic Robotic Bronchoscopy for Evaluation of PulmoNary LEsions: the SERENE Trial

🟡 Not Yet Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol Sponsor: The Cleveland Clinic

🩺 Plain-English Summary (8th-Grade Level)

This is an investigator-initiated, multicenter, non inferiority, cluster randomized controlled trial. The primary objective is to compare the diagnostic yield of the electromagnetic robotic assisted bronchoscopy with digital tomosynthesis (Galaxy system by Noah Medical) to the shape sensing robotic assisted bronchoscopy with integrated cone beam CT (Ion™ Endoluminal System by Intuitive) in patients undergoing bronchoscopy for peripheral pulmonary lesion (PPL) evaluation.

Who can join: Review the eligibility criteria below.

Location: Rush University Medical Center — Chicago, Illinois

Age range: 18 Years

🧪 Interventions in This Study

  • Bronchoscopy for peripheral pulmonary lesion biopsy (PROCEDURE)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (2 Sites)

  • Rush University Medical Center — Chicago, Illinois
  • The Cleveland Clinic — Cleveland, Ohio

📞 Contact the Study Coordinator

Phone: (216) 445-0570

Email: LOWS5@ccf.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Peripheral Pulmonary Lesions (PPLs)

Explore by condition: All Peripheral Pulmonary Lesions (PPLs) clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗