๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-03-24

Exercise and Carotid Artery Function in Metabolic Syndrome (NCT07430839)

Identifying Sex-specific Carotid Endothelial Dysfunction in Young Adults With Metabolic Syndrome

๐ŸŸข Recruiting Interventional Protocol ๐Ÿ“Š Observational Clinical Research Sponsor: University of Wisconsin, Madison

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to determine 1) if young adults with metabolic syndrome display endothelial dysfunction of the internal carotid artery in a sex-specific fashion and 2) if this endothelial dysfunction can be acutely improved with a single bout of exercise. This will be achieved by testing internal carotid artery function before and after a 30-minute bout of moderate intensity exercise. 48 young adults with and without metabolic syndrome will be enrolled and will be on study for approximately 5.5 hours over 4 study visits.

Who can join: Review the eligibility criteria below.

Location: University of Wisconsin โ€” Madison, Wisconsin

Age range: 18 Years to 40 Years

๐Ÿงช Interventions in This Study

  • exercise (BEHAVIORAL)
  • Diagnostics (DIAGNOSTIC_TEST)
  • Inhaled CO2-mixed air (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • University of Wisconsin โ€” Madison, Wisconsin

๐Ÿ“ž Contact the Study Coordinator

Phone: (608) 263-6308

Email: sbolin@wisc.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—