๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-19

Psilocybin Microdosing on Cognition, Mood and Quality of Life (NCT07449351)

Effects of Psilocybin Microdosing on Cognition, Mood and Quality of Life: A Pilot Study

๐ŸŸก Not Yet Recruiting Early Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Yale University

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study is being conducted to evaluate how of 30 days of intermittently microdosed psilocybin affects mood, cognition, subjective well-being and structural/functional MRI results compared to a placebo. Investigators hypothesize that compared to placebo, 30 days of intermittently microdosed psilocybin will produce observable changes in mood, cognition, subjective well-being and MRI, in the absence of psychedelic experiences.

Who can join: Review the eligibility criteria below.

Location: Olin Neuropsychiatry Research Center โ€” Hartford, Connecticut

Age range: 21 Years to 40 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • Olin Neuropsychiatry Research Center โ€” Hartford, Connecticut

๐Ÿ“ž Contact the Study Coordinator

Phone: (860) 545-7757

Email: godfrey.pearlson@hhchealth.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—