๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-03

CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME (NCT07449923)

A Phase 3, Multicenter, Prospective, Randomized, Double-Masked, Parallel-Group Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept (2 mg) in Participants With Diabetic Macular Edema (DME)

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: EyePoint Pharmaceuticals, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a phase 3 randomized, double -masked study comparing the efficacy of EYP-1901 against Aflibercept.

Who can join: Review the eligibility criteria below.

Location: Associated Retina Consultans โ€” Gilbert, Arizona

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (70 Sites)

Showing the first 25 of 70 sites.

  • Associated Retina Consultans โ€” Gilbert, Arizona
  • Associated Retina Consultants - Phoenix โ€” Phoenix, Arizona
  • Phoenix Retina Clinical Trials, LLC - North Phoenix โ€” Phoenix, Arizona
  • Retina Macula Institute of Arizona โ€” Scottsdale, Arizona
  • Retina Vitreous Associates Medical Group โ€” Beverly Hills, California
  • Retina Consultants of Orange County โ€” Fullerton, California
  • South Coast Retina Center โ€” Long Beach, California
  • Retinal Consultants Medical Group - Modesto โ€” Modesto, California
  • Kaiser Permanente โ€” Oakland, California
  • Retina Consultants of Southern California โ€” Redlands, California
  • Bay Area Retina Associates โ€” Walnut Creek, California
  • Retina Specialists of Colorado - Arvada โ€” Arvada, Colorado
  • Connecticut Eye Consultants, P.C. โ€” Danbury, Connecticut
  • Coastal Eye Surgeons, LLC โ€” Greenwich, Connecticut
  • Retina Group of New England, PC โ€” Waterford, Connecticut
  • Retina Group of Florida - Fort Lauderdale โ€” Fort Lauderdale, Florida
  • Retina Specialty Institute โ€” Pensacola, Florida
  • Fort Lauderdale Eye Institute โ€” Plantation, Florida
  • MedEye Associates โ€” South Miami, Florida
  • Retina Vitreous Associates of Florida - Saint Petersburg โ€” St. Petersburg, Florida
  • Retina Vitreous Associates of Florida โ€” Tampa, Florida
  • Retina Associates โ€” Elmhurst, Illinois
  • University Retina and Macula Associates โ€” Lemont, Illinois
  • Illinois Retina Associates, S.C. โ€” Oak Park, Illinois
  • Associated Vitreoretinal & Uveitis Consultants - Carmel โ€” Carmel, Indiana

๐Ÿ“ž Contact the Study Coordinator

Phone: (833) 393-7646

Email: rribeiro@eyepoint.bio

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—