🏛️ Verified NIH Record • Updated 2026-07-14
Efficacy and Safety of Ribupatide (KAI-9531) Administered Once Weekly in Participants Living With Obesity Who Do Not Have Diabetes (NCT07458269)
A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity Who Do Not Have Diabetes
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Kailera
🩺 Plain-English Summary (8th-Grade Level)
The primary objective of this study is to determine the effects of ribupatide administered by subcutaneous (SC) injection once weekly compared to placebo on percent change in body weight.
Who can join: Review the eligibility criteria below.
Location: Kailera Clinical Site — Mesa, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (35 Sites)
Showing the first 25 of 35 sites.
- Kailera Clinical Site — Mesa, Arizona
- Kailera Clinical Site — Sun City West, Arizona
- Kailera Clinical Site — Irvine, California
- Kailera Clinical Site — Lake Forest, California
- Kailera Clinical Site — Lomita, California
- Kailera Clinical Site — Long Beach, California
- Kailera Clinical Site — Montclair, California
- Kailera Clinical Site — Rolling Hills Estates, California
- Kailera Clinical Site — San Diego, California
- Kailera Clinical Site — Santa Ana, California
- Kailera Clinical Site — Van Nuys, California
- Kailera Clinical Site — DeLand, Florida
- Kailera Clinical Site — Orlando, Florida
- Kailera Clinical Site — Orlando, Florida
- Kailera Clinical Site — The Villages, Florida
- Kailera Clinical Site — Decatur, Georgia
- Kailera Clinical Site — Woodstock, Georgia
- Kailera Clinical Site — Morton, Illinois
- Kailera Clinical Site — Indianapolis, Indiana
- Kailera Clinical Site — Louisville, Kentucky
- Kailera Clinical Site — Rockville, Maryland
- Kailera Clinical Site — St Louis, Missouri
- Kailera Clinical Site — Lincoln, Nebraska
- Kailera Clinical Site — Omaha, Nebraska
- Kailera Clinical Site — East Syracuse, New York
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Obesity
- Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools — Tampa, Florida
- SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With Obesity — Tucson, Arizona
- Piloting a Patient Navigator Program for Weight Loss — Philadelphia, Pennsylvania
- Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2) — Mesa, Arizona
- Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects — Orlando, Florida
- Intestinal Metabolic Reprogramming as a Key Mechanism of Gastric Bypass in Humans — Pittsburgh, Pennsylvania
Explore by condition: All Obesity clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.