๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-02

A Study of the Impact of Endocrine Therapy on Surgical Outcomes in People With Lobular Breast Cancer (NCT07483307)

Impact of Neoadjuvant Endocrine Therapy on Surgical Outcomes in Patients With Stage 2 to 3 Invasive Lobular Carcinoma: A Prospective Study

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Memorial Sloan Kettering Cancer Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to look at how effective neoadjuvant (before surgery) endocrine therapy (NET) is in participants with invasive lobular carcinoma (ILC) who have breast-conserving surgery (BCS). The main purpose of the study is to see if NET reduces the chance of having cancer cells at the edges of tissue removed during surgery (positive margins).

Who can join: Review the eligibility criteria below.

Location: Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) โ€” Basking Ridge, New Jersey

Age range: 50 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (7 Sites)

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) โ€” Basking Ridge, New Jersey
  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities) โ€” Middletown, New Jersey
  • Memorial Sloan Kettering Bergen (Limited Protocol Activities) โ€” Montvale, New Jersey
  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) โ€” Commack, New York
  • Memorial Sloan Kettering Westchester (Limited Protocol Activities) โ€” Harrison, New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) โ€” New York, New York
  • Memorial Sloan Kettering Nassau (Limited Protocol Activities) โ€” Uniondale, New York

๐Ÿ“ž Contact the Study Coordinator

Phone: (646) 888-6864

Email: mamtana1@mskcc.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Breast Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—