A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH) (NCT07491458)
A Parallel Treatment Group, Phase 2a, Double-blind, 4-arm Trial to Evaluate the Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Male and Female Participants Aged 30 Years or Older With Metabolic Dysfunction-associated Steatohepatitis (MASH)
🩺 Plain-English Summary (8th-Grade Level)
Rivus Pharmaceuticals. Inc. is sponsoring this research study to assess the safety and tolerability of HU6 as a possible treatment for patients diagnosed with metabolic dysfunction-associated steatohepatitis (MASH). The study will also assess safety, pharmacokinetics (PK) and changes in liver fat content related to patients diagnosed with MASH.
Who can join: Review the eligibility criteria below.
Location: Arizona Liver Health - Chandler — Chandler, Arizona
Age range: 30 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (31 Sites)
Showing the first 25 of 31 sites.
- Arizona Liver Health - Chandler — Chandler, Arizona
- Arizona Liver Health - Peoria — Peoria, Arizona
- Arizona Liver Health - Tucson — Tucson, Arizona
- Baptist Health Center for Clinical Research — Little Rock, Arkansas
- National Institute of Clinical Research — Garden Grove, California
- Catalina Research Institute — Montclair, California
- Knowledge Research Center — Orange, California
- Charter Research LLC - Orlando — Orlando, Florida
- Charter Research LLC - Chicago — Chicago, Illinois
- Delta Research Partners of Bastrop, LLC — Bastrop, Louisiana
- Delta Research Partners of West Monroe, LLC — West Monroe, Louisiana
- Clinical Research Institute of Michigan — Clinton Township, Michigan
- Nucleus Network Minneapolis — Saint Paul, Minnesota
- Kansas City Research Institute — Kansas City, Missouri
- KAD Clinical Research — St Louis, Missouri
- Jubilee Clinical Research, LLC. — Las Vegas, Nevada
- Coastal Research Institute — Fayetteville, North Carolina
- Clinical Research Institute of Ohio, LLC (CRIOH) — Westlake, Ohio
- Tekton Research - Yukon — Yukon, Oklahoma
- Innovative Clinical Research, LLC — Clarksville, Tennessee
- IMA Clinical Research (Austin) — Austin, Texas
- Pinnacle Clinical Research - Austin — Austin, Texas
- Bellaire Clinical Research, LLC — Bellaire, Texas
- Pinnacle Clinical Research - Corpus Christi — Corpus Christi, Texas
- Pinnacle Clinical Research - Georgetown — Georgetown, Texas
📞 Contact the Study Coordinator
Phone: (617) 388-7757
Email: jsoto@rivuspharma.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in MASH - Metabolic Dysfunction-Associated Steatohepatitis
- Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH — La Jolla, California
- Rezdiffra Pregnancy and Lactation Registry — West Conshohocken, Pennsylvania
Explore by condition: All MASH - Metabolic Dysfunction-Associated Steatohepatitis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.