Induced Suppression of Platelet Activity in Aneurysmal Subarachnoid Hemorrhage Management-2 (iSPASM-2) (NCT07493577)
Induced Suppression of Platelet Activity in Aneurysmal Subarachnoid Hemorrhage Management-2
🩺 Plain-English Summary (8th-Grade Level)
An exploratory, randomized, double-blinded, placebo-controlled, two-center clinical trial to determine the maximum tolerated dosage of intravenous tirofiban in patients with aneurysmal subarachnoid hemorrhage (aSAH) post-endovascular coiling. The study will also assess pharmacology and safety, with exploratory endpoints including delayed cerebral ischemia (DCI), vasospasm, and functional outcomes.
Who can join: Review the eligibility criteria below.
Location: Duke University Health System — Durham, North Carolina
Age range: 18 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- Duke University Health System — Durham, North Carolina
- University of Texas Health Sciences Center — Houston, Texas
📞 Contact the Study Coordinator
Phone: (919) 681-4974
Email: hazani.benitez-rosas@duke.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Aneurysmal Subarachnoid Hemorrhage
- Deferoxamine In the Treatment of Aneurysmal Subarachnoid Hemorrhage (aSAH) — Ann Arbor, Michigan
- Nitric Oxide Consumption as a Predictor of Vasospasm in Subarachnoid Hemorrhage — Boston, Massachusetts
- The Effect of Transcutaneous Vagal Nerve Stimulation (tVNS) on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage — Birmingham, Alabama
- Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage — Louisville, Kentucky
- Tocilizumab-aazg for Hemorrhage: Reduction of Ischemic Vascular Events — Gainesville, Florida
Explore by condition: All Aneurysmal Subarachnoid Hemorrhage clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.