Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity (NCT07497880)
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
🩺 Plain-English Summary (8th-Grade Level)
The primary objective of this study is to determine the efficacy of oral KAI-7535 once daily compared with placebo on percent change in body weight in participants living with obesity or overweight, with at least 1 weight-related comorbidity, without diabetes mellitus. Efficacy in participants with type 2 diabetes mellitus will be evaluated. Safety and tolerability and other weight-related outcomes will be evaluated in both types of participants.
Who can join: Review the eligibility criteria below.
Location: Kailera Clinical Site — Chandler, Arizona
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (36 Sites)
Showing the first 25 of 36 sites.
- Kailera Clinical Site — Chandler, Arizona
- Kailera Clinical Site — Phoenix, Arizona
- Kailera Clinical Site — Irvine, California
- Kailera Clinical Site — Lincoln, California
- Kailera Clinical Site — Northridge, California
- Kailera Clinical Site — Hamden, Connecticut
- Kailera Clinical Site — Jacksonville, Florida
- Kailera Clinical Site — Jupiter, Florida
- Kailera Clinical Site — Palm Springs, Florida
- Kailera Clinical Site — Pembroke Pines, Florida
- Kailera Clinical Site — Decatur, Georgia
- Kailera Clinical Site — Chicago, Illinois
- Kailera Clinical Site — Skokie, Illinois
- Kailera Clinical Site — South Bend, Indiana
- Kailera Clinical Site — Kenner, Louisiana
- Kailera Clinical Site — Garden City, Michigan
- Kailera Clinical Site — Jefferson City, Missouri
- Kailera Clinical Site — Kansas City, Missouri
- Kailera Clinical Site — Spartanburg, South Carolina
- Kailera Clinical Site — Knoxville, Tennessee
- Kailera Clinical Site — Austin, Texas
- Kailera Clinical Site — Austin, Texas
- Kailera Clinical Site — Brownsville, Texas
- Kailera Clinical Site — Farmers Branch, Texas
- Kailera Clinical Site — Fort Worth, Texas
📞 Contact the Study Coordinator
Phone: (781) 317-0291
Email: info-clinicalstudies@kailera.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.