๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-26

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets (NCT07502495)

A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial Assessing the Efficacy and Safety of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets Despite Antihyperglycemic Medications

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Biomea Fusion Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a Phase 2, randomized, double-blind, placebo-controlled trial assessing the efficacy and safety of icovamenib in participants with Type 2 Diabetes who are not achieving glycemic targets despite antihyperglycemic medications.

Who can join: Review the eligibility criteria below.

Location: Central Research Associates, LLC dba Flourish Research โ€” Birmingham, Alabama

Age range: 18 Years to 75 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (18 Sites)

  • Central Research Associates, LLC dba Flourish Research โ€” Birmingham, Alabama
  • Hope Clinical Research โ€” Canoga Park, California
  • Ark Clinical Research โ€” Fountain Valley, California
  • Ark Clinical Research โ€” Long Beach, California
  • Catalina Research Institute, LLC โ€” Montclair, California
  • Paradigm Clinical Research Centers, LLC โ€” San Diego, California
  • Southwest General Healthcare Center โ€” Fort Myers, Florida
  • Panax Clinical Research โ€” Miami Lakes, Florida
  • Clinical Site Partners, LLC dba Flourish Research โ€” Winter Park, Florida
  • David Kavtaradze MD, Inc โ€” Cordele, Georgia
  • Excel Clinical Research โ€” Las Vegas, Nevada
  • Diabetes and Endocrinology Associates of Stark County โ€” Canton, Ohio
  • Elligo Health Research, Inc. โ€” Austin, Texas
  • Zenos Clinical Research โ€” Dallas, Texas
  • Synergy Groups Medical โ€” Houston, Texas
  • Epic Clinical Research โ€” Lewisville, Texas
  • Synergy Group Medical LLC โ€” Missouri City, Texas
  • Manassas Clinical Research Center โ€” Manassas, Virginia

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Type 2 Diabetes clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—