AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss (NCT07503210)
Efficacy and Safety of NNC0487-0111 s.c. Once Weekly in Participants With Obesity Who Have Reached Target Dose During run-in Period (AMAZE 12)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.
Who can join: Review the eligibility criteria below.
Location: Pinnacle Research Group LLC — Anniston, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (72 Sites)
Showing the first 25 of 72 sites.
- Pinnacle Research Group LLC — Anniston, Alabama
- Diablo Clinical Research, Inc. — Walnut Creek, California
- Florida Inst For Clin Res LLC — Orlando, Florida
- Endeavor Health — Skokie, Illinois
- Midwest Inst For Clin Res — Indianapolis, Indiana
- Medication Mgmnt, LLC_Grnsboro — Greensboro, North Carolina
- PMG Research of Wilmington LLC — Wilmington, North Carolina
- UPA Ctr Weight and Eating Dis — Philadelphia, Pennsylvania
- Clinical Res Collaborative — Cumberland, Rhode Island
- North Texas Endocrine Center — Dallas, Texas
- UT Southwestern Med Cntr — Dallas, Texas
- Selma Medical Associates — Winchester, Virginia
- Rainier Clin Res Ctr Inc — Renton, Washington
- Conexa — Ciudad Autonoma de Buenos Aires, Buenos Aires
- CICEMO- Consultorio (Av Directorio) — Ciudad Autónoma de Buenos Aires, Buenos Aires
- Instituto de Investigaciones Clinicas Mar Del Plata — Mar del Plata, Buenos Aires
- CIPREC Pueyrredon — Buenos Aires,
- Sydney Clinical Trials — Campbelltown, New South Wales
- Sydney Cardiometabolic Centre — Liverpool, New South Wales
- Hunter Diabetes Centre — Merewether, New South Wales
- Nightingale Research Adelaide — Adelaide, South Australia
- Anima Research Center — Diepenbeek,
- AZ Groeninge - Kortrijk - Centrum Endo - Diabetologie — Kortrijk,
- Centre hospitalier universitaire de Liège (CHU de Liège) — Liège,
- AZ OOSTENDE (Campus DAMIAAN) — Ostend,
📞 Contact the Study Coordinator
Phone: (866) 867-7178
Email: clinicaltrials@novonordisk.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.