Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension (NCT07511361)
A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Two-Part Study to Evaluate the Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the blood pressure-lowering effect of tonlamarsen in adult participants who were recently hospitalized and concurrently experienced an episode of acute severe hypertension.
Who can join: Review the eligibility criteria below.
Location: Western Nephrology and Metabolic Bone Disease, PC - Arvada — Arvada, Colorado
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (8 Sites)
- Western Nephrology and Metabolic Bone Disease, PC - Arvada — Arvada, Colorado
- Homestead Associates in Research — Homestead, Florida
- Progressive Medical Research — Port Orange, Florida
- Richmond University Medical Center (RUMC) — Staten Island, New York
- Research Innovations, LLC — Beavercreek, Ohio
- Chattanooga Research & Medicine CHARM — Chattanooga, Tennessee
- Laguna Clinical Research Associates — Laredo, Texas
- Baylor Scott and White Research Institute - Temple — Temple, Texas
📞 Contact the Study Coordinator
Phone: (877) 310-5135
Email: clinicaltrials@kardigan.bio
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.