Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE) (NCT07528690)
Microbiota Transplant Therapy to Prevent HE Recurrence in a Phase 2B Multi-Center Trial of Veterans With Cirrhosis
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to find out whether changing the microbes in the bowels of Veterans with cirrhosis and hepatic encephalopathy (a condition that affects the brain as a result of liver problems) using capsules made from microbes from healthy people can prevent future episodes of hepatic encephalopathy.
Who can join: Review the eligibility criteria below.
Location: CERC (VISN1, West Haven, CT) — West Haven, Connecticut
Age range: 21 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- CERC (VISN1, West Haven, CT) — West Haven, Connecticut
- VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX — Dallas, Texas
- Richmond VA Medical Center, Richmond, VA — Richmond, Virginia
📞 Contact the Study Coordinator
Phone: (804) 675-5802
Email: Jasmohan.Bajaj@va.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hepatic Encephalopathy
- Evaluation of Rifaximin SSD for Delaying Encephalopathy Decompensation in Patients With Cirrhosis — Homewood, Alabama
- Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis — Dothan, Alabama
- Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy — Boston, Massachusetts
- Revealing Engagement Patterns Among Hepatic Encephalopathy Patients — San Francisco, California
- Endoscopic Shunts Embolization for Refractory Hepatic Encephalopathy — Newark, New Jersey
Explore by condition: All Hepatic Encephalopathy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.