A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity (NCT07567001)
Efficacy and Safety of NNC0487-0111 Compared to Placebo on Morbidity and Mortality in People With Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
🩺 Plain-English Summary (8th-Grade Level)
This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo. The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have HFpEF or HFmrEF and excess body weight. Participants will get NNC0487-0111 or placebo by injection once a week. Which treatment participants get is decided by chance. NNC0487-0111 is a new medicine that doctors cannot prescribe yet, but it has been tested in people before.
Who can join: Review the eligibility criteria below.
Location: Advanced Cardiovascular, LLC — Alexander City, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (838 Sites)
Showing the first 25 of 838 sites.
- Advanced Cardiovascular, LLC — Alexander City, Alabama
- Univ of Alabama Birmingham — Birmingham, Alabama
- Eastern Shore Rsrch Inst, LLC — Fairhope, Alabama
- Mobile Heart USA Health Cardiology Clinic — Mobile, Alabama
- Mercy Gilbert Medical Center — Gilbert, Arizona
- Sun City Clinical Research — Glendale, Arizona
- Honor Health — Phoenix, Arizona
- Arizona Research Center — Phoenix, Arizona
- Arkansas Health Group — Little Rock, Arkansas
- InvivoCure -2 — Alhambra, California
- Cardio Research of S. Cal — Beverly Hills, California
- Westside Medical Associates Los Angeles — Beverly Hills, California
- Scripps Hospital — Chula Vista, California
- John Muir Physicians Network — Concord, California
- Valley Clinical Trials — Covina, California
- Mission Cardiovascular Research Institute — Fremont, California
- Amicis Research Center — Granada Hills, California
- California Heart Specialist — Huntington Beach, California
- Valiance Clinical Research — Huntington Park, California
- Joe C.Wen & Fam CTR for Adv Care — Irvine, California
- Scripps Memorial Hospital La Jolla — La Jolla, California
- UCSD NAFLD Research Center — La Jolla, California
- Cardio Innovation & Resch Ctr — Long Beach, California
- Pacific Clinical Studies — Los Alamitos, California
- VAGrtrLosAngelesHlthcareSystem — Los Angeles, California
📞 Contact the Study Coordinator
Phone: (866) 867-7178
Email: clinicaltrials@novonordisk.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.