๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-05

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight (NCT07589608)

A Phase 2b, Parallel-Group, Double-Blind, Placebo-Controlled Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight and Without Type 2 Diabetes

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to examine the body weight-lowering efficacy and safety of macupatide plus eloralintide compared with placebo in participants with obesity or overweight and without type 2 diabetes. Participation will last about 64 weeks.

Who can join: Review the eligibility criteria below.

Location: The Institute for Liver Health II dba Arizona Clinical Trials - Mesa โ€” Chandler, Arizona

Age range: 18 Years to 75 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (40 Sites)

Showing the first 25 of 40 sites.

  • The Institute for Liver Health II dba Arizona Clinical Trials - Mesa โ€” Chandler, Arizona
  • Headlands Research - Scottsdale โ€” Scottsdale, Arizona
  • The Institute for Liver Health II dba Arizona Liver Health-Tucson โ€” Tucson, Arizona
  • NorCal Medical Research, Inc โ€” Greenbrae, California
  • Velocity Clinical Research, Huntington Park โ€” Huntington Park, California
  • Peninsula Research Associates โ€” Rolling Hills Estates, California
  • Diablo Clinical Research, Inc. โ€” Walnut Creek, California
  • Stamford Therapeutics Consortium โ€” Stamford, Connecticut
  • New Horizon Research Center โ€” Miami, Florida
  • Indago Research & Health Center, Inc โ€” Miami Lakes, Florida
  • Suncoast Clinical Research, Inc. โ€” New Port Richey, Florida
  • Charter Research - Winter Park โ€” Orlando, Florida
  • Charter Research - Lady Lake โ€” The Villages, Florida
  • Medical Research Partners โ€” Ammon, Idaho
  • Great Lakes Clinical Trials - Ravenswood โ€” Chicago, Illinois
  • Cotton O'Neil Diabetes & Endocrinology โ€” Topeka, Kansas
  • Monroe Biomedical Research - Louisville โ€” Louisville, Kentucky
  • Knownwell โ€” Needham, Massachusetts
  • Lucida Clinical Trials โ€” New Bedford, Massachusetts
  • Headlands Research - Detroit โ€” Southfield, Michigan
  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division โ€” Troy, Michigan
  • StudyMetrix Research โ€” City of Saint Peters, Missouri
  • Clinvest Headlands Llc โ€” Springfield, Missouri
  • Las Vegas Medical Research โ€” Las Vegas, Nevada
  • Dent Neurologic Institute โ€” Amherst, New York

๐Ÿ“ž Contact the Study Coordinator

Phone: (317) 615-4559

Email: LillyTrials@Lilly.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Overweight clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—