A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis (NCT07598396)
A Phase II Open-Label Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Mosunetuzumab in Patients With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis
🩺 Plain-English Summary (8th-Grade Level)
This study will assess how mosunetuzumab works in people who have systemic lupus erythematosus (SLE) who may or may not also have active lupus nephritis (LN).
Who can join: Review the eligibility criteria below.
Location: Clnica SER da Bahia — Salvador, Estado de Bahia
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (21 Sites)
- Clnica SER da Bahia — Salvador, Estado de Bahia
- L2IP ?Instituto de Pesquisas Clínicas Ltda. — Brasília, Federal District
- IPC MT Instituto de Pesquisas Clinicas do Mato Grosso — Cuiab, Mato Grosso
- Complexo Hospitalar de Niteroi — Niterói, Rio de Janeiro
- LMK Servios Mdicos S/S Ltda — Porto Alegre, Rio Grande do Sul
- Hospital das Clinicas de Ribeirao Preto — Ribeiro Preto, São Paulo
- Hospital das Clnicas da Faculdade de Medicina da USP — São Paulo, São Paulo
- Clinica de la Costa S.A.S — Barranquilla,
- Administradora Country S.A.S. — Bogotá,
- Centro de Investigacion en Reumatologia y Especialdades Medicas SAS. CIREEM — Bogotá,
- Hospital Pablo Tobon Uribe — Medellín,
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS — Rome, Lazio
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili) — Brescia, Lombardy
- Istituto Clinico Humanitas — Rozzano, Lombardy
- CIMAB S.A. de C.V. — Torreón, Coahuila
- Centro Medico del Angel — Mexicali, Estado de Baja California
- Centro de Investigación y Tratamiento Reumatológico S.C. — México, Mexico CITY (federal District)
- Centro de Investigación de Tratamientos Innovadores de Sinaloa (CITI) — Culiacán, Sinaloa
- Emmed Research — Pretoria, Gauteng
- University of Cape Town Kidney and Hypertension Research Unit — Cape Town, Western Cape
- Clinical Trials Network Helderberg — Somerset West, Western Cape
📞 Contact the Study Coordinator
Phone: (888) 662-6728
Email: global-roche-genentech-trials@gene.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Complete Cognitive Intervention for cSLE — Toronto, Ontario
- Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Lupus — St John's,
Explore by condition: All Lupus clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.