A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure (NCT07615010)
Phase 2 Adaptive Randomized, Placebo -Controlled Trial of agenT-797 + Standard of Care Vs. Placebo + Standard of Care in Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure (AHRF) By Global ARDS Criteria
🩺 Plain-English Summary (8th-Grade Level)
This clinical trial will evaluate the efficacy and safety of a single intravenous dose of agenT-797 administered in addition to standard of care (SOC), compared with placebo plus SOC, in reducing short-term mortality in adult participants with severe pneumonia and moderate to severe AHRF. All participants will receive SOC management for severe pneumonia and acute respiratory distress syndrome (ARDS).
Who can join: Review the eligibility criteria below.
Location: UCSF Medical Center at Parnassus Heights — San Francisco, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (4 Sites)
- UCSF Medical Center at Parnassus Heights — San Francisco, California
- Children's Memorial Hermann Hospital — Houston, Texas
- University Hospital — San Antonio, Texas
- First Lviv Territorial Medical Union — Lviv,
📞 Contact the Study Coordinator
Phone: (212) 994-8250
Email: webmaster@minktherapeutics.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Pneumonia
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- Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P Trial — Birmingham, Alabama
- Study of Lung Proteins in Patients With Pneumonia — Bethesda, Maryland
- Performance of New Diagnostic Methods in Older Adults With Pneumonia — Columbus, Ohio
- How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care. — Bloomsburg, Pennsylvania
- Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial — Phoenix, Arizona
Explore by condition: All Pneumonia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.