Who is eligible for clinical trial NCT07624305?

Participants must meet protocol criteria for Renal Insufficiency, Chronic. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT07624305 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-05-29

A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD) (NCT07624305)

A Phase III, Randomised, Double-blind, Study to Evaluate the Effect of Balcinrenone/Dapagliflozin Compared With Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Chronic Kidney Disease (Stage 3b and 4)

🟡 Not Yet Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: AstraZeneca

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the efficacy, safety and tolerability of balcinrenone in fixed combination with dapagliflozin, compared with dapagliflozin, in patients with CKD Stage 3b and 4 (eGFR ≥ 15 to \< 45 mL/min/1.73 m2) administered orally once daily in addition to SoC. This is a population with high unmet medical need and an increased risk of CKD progression, who are frequently excluded from interventional trials.

Who can join: Review the eligibility criteria below.

Location: Research Site — Ciudad de Buenos Aires

Age range: 18 Years to 99 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (45 Sites)

Showing the first 25 of 45 sites.

Research Site — Ciudad de Buenos Aires,
Research Site — Edmonton, Alberta
Research Site — Winnipeg, Manitoba
Research Site — London, Ontario
Research Site — Toronto, Ontario
Research Site — Waterloo, Ontario
Research Site — Halifax,
Research Site — Magdeburg,
Research Site — Kita-ku,
Research Site — Osaka,
Research Site — Olsztyn,
Research Site — Warsaw,
Research Site — Warsaw,
Research Site — Węgrów,
Research Site — Wroclaw,
Research Site — Żywiec,
Research Site — Anyang,
Research Site — Cheonan-si,
Research Site — Seoul,
Research Site — Seoul,
Research Site — Seoul,
Research Site — Seoul,
Research Site — Seoul,
Research Site — Changhua,
Research Site — Hualien City,

📞 Contact the Study Coordinator

Phone: (877) 240-9479

Email: information.center@astrazeneca.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Renal Insufficiency, Chronic

SDCC - Prospective Cohort Study of Chronic Renal Insufficiency — Oakland, California
Neurovascular Transduction During Exercise in Chronic Kidney Disease — Atlanta, Georgia

Explore by condition: All Renal Insufficiency, Chronic clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Contact the study coordinator using the phone/email above.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗