๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-03

Nebulized AER101 in Pre-op NSCLC (NCT07631299)

Nebulized AER101 to Inhibit Glycolysis for Pre-Operative Non-small Cell Lung Cancer (NSCLC)

๐ŸŸก Not Yet Recruiting Early Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: University of Oklahoma

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The primary objective of this pilot study is to determine if AER101 can decrease glycolysis in non-small cell lung cancer (NSCLC). Glycolysis is the process cells use to break down sugar (glucose) into a smaller substance in the fluid part inside the cell. Many lung cancers begin in bronchi, bronchioles and alveoli cells surrounding the airways, which enables nebulization to deposit AER101 on lung tumors. Participants in the study will self-administer AER101 via a hand-held personal nebulizer three times per day (dosing at least 4 hours apart) for 14 days prior to undergoing surgery for lung cancer.

Who can join: Review the eligibility criteria below.

Location: OU Medical Center Hospital โ€” Oklahoma City, Oklahoma

Age range: 18 Years to 100 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (2 Sites)

  • OU Medical Center Hospital โ€” Oklahoma City, Oklahoma
  • Stephenson Cancer Center โ€” Oklahoma City, Oklahoma

๐Ÿ“ž Contact the Study Coordinator

Phone: (405) 271-8001

Email: theresa-lander@ou.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—