๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-31

WATER IV PCa (AS Sub-study) (NCT07650448)

WATER IV Prostate Cancer: Aquablation Versus Active Surveillance for the Treatment of Localized Prostate Cancer

๐ŸŸก Not Yet Recruiting Observational / Diagnostic โš™๏ธ Medical Device Protocol Sponsor: PROCEPT BioRobotics

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The WATER IV study is a multicenter, prospective, randomized clinical trial that aims to evaluate the safety and efficacy of Aquablation therapy in men with localized prostate cancer.

Who can join: Review the eligibility criteria below.

Location: Arizona Clinical Trials โ€” Chandler, Arizona

Age range: 45 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (25 Sites)

  • Arizona Clinical Trials โ€” Chandler, Arizona
  • University of Southern California โ€” Los Angeles, California
  • Tri Valley Urology โ€” Murrieta, California
  • Boulder Medical Center โ€” Boulder, Colorado
  • Advanced Research โ€” Delray Beach, Florida
  • University of Miami โ€” Miami, Florida
  • Georgia Urology โ€” Atlanta, Georgia
  • Mountain View Hospital โ€” Idaho Falls, Idaho
  • University of Chicago โ€” Chicago, Illinois
  • Endeavor Health โ€” Glenview, Illinois
  • Johns Hopkins University โ€” Baltimore, Maryland
  • Kansas City Urology Care โ€” North Kansas City, Missouri
  • Kearney Urology Center โ€” Kearney, Nebraska
  • Adult & Pediatric Urology โ€” Omaha, Nebraska
  • Hackensack University Medical Center โ€” Hackensack, New Jersey
  • Albany Medical College โ€” Albany, New York
  • Integrated Medical Professionals, PLLC โ€” New York, New York
  • University of Rochester Medical Center โ€” Rochester, New York
  • Cleveland Clinic Foundation โ€” Cleveland, Ohio
  • MUSC Hollings Cancer Center โ€” Charleston, South Carolina
  • Tidelands Health Urology โ€” Murrells Inlet, South Carolina
  • Urology Austin โ€” Austin, Texas
  • Urology Clinics of North Texas โ€” Dallas, Texas
  • Advocate Aurora Research Institute โ€” Sheboygan, Wisconsin
  • Chinese University of Hong Kong โ€” Shatin,

๐Ÿ“ž Contact the Study Coordinator

Phone: (650) 232-7215

Email: a.lee@procept-biorobotics.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—