TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE) (NCT07653594)
TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE): A Single Arm Pilot Study
🩺 Plain-English Summary (8th-Grade Level)
Participants may take part in this study if they are scheduled to undergo a surgery that meets the following: (1) traditional open surgery via laparotomy, (2) length of surgery \>3 hours, and (3) curative-intent surgical resection of a cancer in the stomach, pancreas, bile ducts, liver, or peritoneal surfaces. The purpose of this study is (1) to evaluate the feasibility of collecting blood samples prior to surgery, post-surgery and pre- music-assisted relaxation and imagery (MARI) intervention, and immediately post-MARI intervention and (2) to identify gene expression changes associated with MARI and explore their relationship with immediate changes in pain intensity. Participants will be in this study for the duration of their hospital admission for surgery.
Who can join: Review the eligibility criteria below.
Location: University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center — Cleveland, Ohio
Age range: 50 Years to 80 Years
🧪 Interventions in This Study
- Music-assisted relaxation and imagery (MARI) (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center — Cleveland, Ohio
📞 Contact the Study Coordinator
Phone: (216) 844-7727
Email: Samuel.RodgersMelnick@UHhospitals.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Surgery
- Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology-3 Trial — Hamilton, Ontario
- Buccal Graft + Collagen Matrix Versus Free Gingival Graft for Keratinized Mucosa Augmentation at Implant Sites — Boston, Massachusetts
- Circadian Rhythm Disruption in the Hospital Intensive Care Environment — Philadelphia, Pennsylvania
- Operating Room Air Filtration/Sterilization — Cleveland, Ohio
- Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments — Madison, Wisconsin
- Differences in Radial and Ulnar Artery Size in Young Children — Columbus, Ohio
Explore by condition: All Surgery clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.