A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) (NCT07654374)
A Long-Term Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Multiple Maintenance Doses of Oral Once Daily Aleniglipron for Chronic Weight Management in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
🩺 Plain-English Summary (8th-Grade Level)
This is randomized, double-blind, placebo-controlled study of the long-term efficacy, safety, and tolerability of multiple doses of aleniglipron in participants living with overweight or obesity and T2DM. Participants will be randomized to aleniglipron or placebo for a total of 76 weeks of treatment.
Who can join: Review the eligibility criteria below.
Location: ACCOMPLISH-2 Research Site — Birmingham, Alabama
Age range: 18 Years to 79 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (74 Sites)
Showing the first 25 of 74 sites.
- ACCOMPLISH-2 Research Site — Birmingham, Alabama
- ACCOMPLISH-2 Research Site — Chandler, Arizona
- ACCOMPLISH-2 Research Site — Phoenix, Arizona
- ACCOMPLISH-2 Research Site — Sun City West, Arizona
- ACCOMPLISH-2 Research Site — Tucson, Arizona
- ACCOMPLISH-2 Research Site — Little Rock, Arkansas
- ACCOMPLISH-2 Research Site — Escondido, California
- ACCOMPLISH-2 Research Site — Fountain Valley, California
- ACCOMPLISH-2 Research Site — Lake Forest, California
- ACCOMPLISH-2 Research Site — Rolling Hills Estates, California
- ACCOMPLISH-2 Research Site — San Diego, California
- ACCOMPLISH-2 Research Site — San Diego, California
- ACCOMPLISH-2 Research Site — Tustin, California
- ACCOMPLISH-2 Research Site — Waterbury, Connecticut
- ACCOMPLISH-2 Research Site — Clearwater, Florida
- ACCOMPLISH-2 Research Site — Fort Myers, Florida
- ACCOMPLISH-2 Research Site — Jacksonville, Florida
- ACCOMPLISH-2 Research Site — Leesburg, Florida
- ACCOMPLISH-2 Research Site — Miami, Florida
- ACCOMPLISH-2 Research Site — Ocala, Florida
- ACCOMPLISH-2 Research Site — Ocoee, Florida
- ACCOMPLISH-2 Research Site — Pembroke Pines, Florida
- ACCOMPLISH-2 Research Site — Atlanta, Georgia
- ACCOMPLISH-2 Research Site — Columbus, Georgia
- ACCOMPLISH-2 Research Site — Lawrenceville, Georgia
📞 Contact the Study Coordinator
Phone: (650) 457-1959
Email: GSBRClinicalTrials@structuretx.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.