🏛️ Verified NIH Record • Updated 2026-06-16
211At-MABG in Adults With Advanced Neuroendocrine Cancers (NCT07661420)
🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic Sponsor: University of Pennsylvania
🩺 Plain-English Summary (8th-Grade Level)
Phase I dose escalation study of 211At-MABG in adults with advanced pheochromocytoma / paraganglioma (PPGL) or other NET-overexpressing cancers (as evidenced by positive MIBG imaging) who are refractory to, lacking, or ineligible for approved treatments. Phase 1 dose-escalation will follow a standard 3+3 design with an expansion cohort at the recommended phase two dose (RP2D).
Who can join: Review the eligibility criteria below.
Location: University of Pennsylvania - Abramson Cancer Center — Philadelphia, Pennsylvania
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Pennsylvania - Abramson Cancer Center — Philadelphia, Pennsylvania
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Pheochromocytoma
- Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma — New York, New York
- Zanzalintinib in Unresectable and Progressive MPGGs — Boston, Massachusetts
- Diagnosis of Pheochromocytoma — Bethesda, Maryland
- Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions — San Antonio, Texas
- Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma — Bethesda, Maryland
Explore by condition: All Pheochromocytoma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.