๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-07

A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes (NCT07668388)

Efficacy and Safety of Once-weekly Subcutaneous UBT251 in Participants With Type 2 Diabetes - a Dose-finding Study

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Novo Nordisk A/S

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The study is testing UBT251 in participants with type 2 diabetes. The purpose of this clinical study is to find out if UBT251 is effective and safe for treating participants with type 2 diabetes. Participants will either get UBT251, UBT251 placebo, semaglutide, or semaglutide placebo. Which treatment participants get is decided by chance. UBT251 is the treatment being tested and is not yet available for doctors to prescribe, while semaglutide is a medicine used to treat type 2 diabetes that doctors can already prescribe.

Who can join: Review the eligibility criteria below.

Location: Flourish Research โ€” Birmingham, Alabama

Age range: 18 Years to 75 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (70 Sites)

Showing the first 25 of 70 sites.

  • Flourish Research โ€” Birmingham, Alabama
  • Ark Clinical Research โ€” Fountain Valley, California
  • Ark Clinical Research โ€” Long Beach, California
  • Los Angeles Institute for Metabolic Research โ€” Los Angeles, California
  • Catalina Research Institute, LLC โ€” Montclair, California
  • Encore Medical Research LLC โ€” Hollywood, Florida
  • South Broward Research LLC โ€” Miramar, Florida
  • Encore Medical Research of Weston โ€” Weston, Florida
  • Midwest Inst For Clin Res โ€” Indianapolis, Indiana
  • Cotton O'Neil Diabetes & Endocrinology โ€” Topeka, Kansas
  • MD Medical Research โ€” Oxon Hill, Maryland
  • PharmQuest โ€” Greensboro, North Carolina
  • KDCILM, LLC & Accellacare US, Inc. โ€” Wilmington, North Carolina
  • Plains Clinical Research Center, LLC_Fargo โ€” Fargo, North Dakota
  • Preferred Primary Care Physicians, Inc. โ€” Uniontown, Pennsylvania
  • Monroe Biomedical Research, LLC โ€” North Charleston, South Carolina
  • LifeDoc Health โ€” Memphis, Tennessee
  • IMA Clinical Research โ€” Austin, Texas
  • Private Practice - Dr. Laila A. Hassan โ€” Houston, Texas
  • Radiance Clinical Research โ€” Lampasas, Texas
  • Quality Research Inc โ€” San Antonio, Texas
  • Tekton Research Inc โ€” San Antonio, Texas
  • Consano Clin Res-Shavano Park โ€” Shavano Park, Texas
  • Chrysalis Clinical Research โ€” St. George, Utah
  • The Vancouver Clinic โ€” Vancouver, Washington

๐Ÿ“ž Contact the Study Coordinator

Phone: (866) 867-7178

Email: clinicaltrials@novonordisk.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—