🏛️ Verified NIH Record • Updated 2026-08-24
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide (NCT07668414)
Efficacy and Safety of Zenagamtide s.c. Once-weekly Compared to Semaglutide s.c. Once-weekly in Participants With Obesity (AMAZE 7)
🟡 Not Yet Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Novo Nordisk A/S
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to find out if zenagamtide is safe and effective for treating participants who have excess body weight compared to treatment with semaglutide.
Who can join: Review the eligibility criteria below.
Location: First Valley Medical Group — Lancaster, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (43 Sites)
Showing the first 25 of 43 sites.
- First Valley Medical Group — Lancaster, California
- Desert Oasis Healthcare — Palm Springs, California
- Western University of Health Sciences — Pomona, California
- Artemis Insitute for Clin Res — San Diego, California
- Med Home Development Grp — Washington D.C., District of Columbia
- Encore Medical Research LLC — Hollywood, Florida
- NextPhase Research — Hollywood, Florida
- Jacksonville Ctr Clin Res — Jacksonville, Florida
- PharmaDev Clinical Research Institute LLC — Miami, Florida
- South Broward Research LLC — Miramar, Florida
- Essence MD Research — Naples, Florida
- Florida Inst For Clin Res LLC — Orlando, Florida
- Oviedo Medical Research, LLC — Oviedo, Florida
- Palm Beach Research Center — West Palm Beach, Florida
- Encore Medical Research of Weston — Weston, Florida
- Conquest Research — Atlanta, Georgia
- Eastside Bariatric and Gen Surg — Snellville, Georgia
- Chicago Research Center, Inc — Chicago, Illinois
- Endeavor Health — Skokie, Illinois
- Midwest Inst For Clin Res — Indianapolis, Indiana
- Southern Clin Research — Zachary, Louisiana
- Amicis Centers of Clinical Research — St Louis, Missouri
- Ichor Research — Syracuse, New York
- Southgate Medical Group, LLP — West Seneca, New York
- Lillestol Research LLC — Fargo, North Dakota
📞 Contact the Study Coordinator
Phone: (866) 867-7178
Email: clinicaltrials@novonordisk.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.