🏛️ Verified NIH Record • Updated 2026-08-19
Real-World Effectiveness of RSV Vaccines Among Adults Using Target Trial Emulation in Epic Cosmos (NCT07673081)
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Pfizer
🩺 Plain-English Summary (8th-Grade Level)
Among non-pregnant adults observed in Epic Cosmos since August 2023 who are eligible for RSV vaccination, what is the effectiveness of ABRYSVO® (RSVpreF), compared with unvaccinated individuals, in preventing RSV-related and all-cause acute respiratory illness (ARI), lower respiratory tract disease (LRTD), and other outcomes of interest, within a target trial emulation (TTE) framework
Who can join: Review the eligibility criteria below.
Location: Pfizer — New York, New York
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Pfizer — New York, New York
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Respiratory Syncytial Virus (RSV)
- A Phase 1 Study to Evaluate JCXH-108, an mRNA-based Vaccine Against RSV — Jupiter, Florida
- Evaluating ABRYSVO Maternal Vaccine Effectiveness Among Infants — New York, New York
- Systems Biological Analysis of Immune Responses to RSV Vaccine — Decatur, Georgia
- A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Immunocompromised Adults — Rochester, New York
- RSV Vaccine Pregnancy Registry — Wilmington, North Carolina
Explore by condition: All Respiratory Syncytial Virus (RSV) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.