๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-26

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION) (NCT07684235)

A Phase 3, Randomized, Double-Blind Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Participants With Obesity or Overweight

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Amgen

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The primary objective of this trial is to evaluate the long-term efficacy, safety, and tolerability of maridebart cafraglutide in participants with obesity or overweight. Trial 20250197 is an extension of trial 20210181 (NCT06858839).

Who can join: Review the eligibility criteria below.

Location: Pinnacle Research Group LLC โ€” Anniston, Alabama

Age range: 18 Years to 99 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (83 Sites)

Showing the first 25 of 83 sites.

  • Pinnacle Research Group LLC โ€” Anniston, Alabama
  • Alliance For Multispecialty Research - Daphne โ€” Daphne, Alabama
  • Alliance for Multispecialty Research Mobile โ€” Mobile, Alabama
  • Ark Clinical Research- Tustin โ€” Fountain Valley, California
  • Long Beach Clinical Trials Services Inc โ€” Long Beach, California
  • Ark Clinical Research- Long Beach โ€” Long Beach, California
  • Catalina Research Institute โ€” Montclair, California
  • Artemis Institute for Clinical Research โ€” Riverside, California
  • Apex Clinical Research โ€” San Diego, California
  • Artemis Institute for Clinical Research โ€” San Diego, California
  • Southern California Clinical Research โ€” Santa Ana, California
  • Diablo Clinical Research โ€” Walnut Creek, California
  • Chase Medical Research LLC โ€” Waterbury, Connecticut
  • Jacksonville Center for Clinical Research โ€” Jacksonville, Florida
  • Clinical Neuroscience Solutions - Jacksonville โ€” Jacksonville, Florida
  • South Florida Wellness and Clinical Research Institute โ€” Margate, Florida
  • Optimus U Corporation โ€” Miami, Florida
  • Research Institute of South Florida โ€” Miami, Florida
  • Indago Research and Health Center โ€” Miami Lakes, Florida
  • Renstar Medical Research โ€” Ocala, Florida
  • Clinical Neuroscience Solutions - Orlando โ€” Orlando, Florida
  • Combined Research Orlando Phase I IV โ€” Orlando, Florida
  • Florida Institute for Clinical Research โ€” Orlando, Florida
  • Encore Medical Research of Weston LLC โ€” Weston, Florida
  • Center for Advanced Research and Education โ€” Gainesville, Georgia

๐Ÿ“ž Contact the Study Coordinator

Phone: (866) 572-6436

Email: medinfo@amgen.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Obesity clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—