NeuroRise: Intrathecal CE-1 Treatment for Traumatic SCI (NCT07739043)
A Single-Arm and Open Labeled Clinical Study of CE1 (Allogeneic Umbilical Cord-Derived Mesenchymal Stem Cells, or UC-MSC) in Traumatic Spinal Cord Injury Patients Within Ten Years of Injury
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess the safety and tolerability of intrathecal administration of CE-1 at a weight-based dose (cells/kg BW), capped at a maximum total dose of 1×10⁸ cells in 10 mL, with administered volume calculated using M = 0.167 mL/kg BW. Study details include: The overall study duration will be up to three years. The primary endpoint will be assessed at 6 months following investigational product administration. An additional secondary endpoint will be assessed at 12 months in the form of a phone call. Study visits therefore consist of one interventional visit, an evaluation visit within two weeks post-injection, a primary endpoint follow-up visit at 6 months, and a secondary endpoint follow-up phone call at 12-months.
Who can join: Review the eligibility criteria below.
Location: The University of Chicago — Chicago, Illinois
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- The University of Chicago — Chicago, Illinois
📞 Contact the Study Coordinator
Phone: (507) 218-7764
Email: fatima.soltan@neuroinnovations.co
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in SCI - Spinal Cord Injury
- Nutrition and Pain Study — Miami, Florida
- Improving Balance After Spinal Cord Injury Using a Robotic Upright Stand Trainer and Spinal Cord Epidural Stimulation — West Orange, New Jersey
- Double Dose 4-AP on Functional Recovery After Spinal Cord Injury — Chicago, Illinois
- Home-Based Heat Therapy in Spinal Cord Injury to Improve Cardiovascular Health — San Antonio, Texas
- Food Intake and Thermogenesis in High Spinal Cord Injury — Miami, Florida
Explore by condition: All SCI - Spinal Cord Injury clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.