๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-12

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes (NCT07743450)

A Phase III, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Once-Daily Oral ASC30 in Adult Participants With Obesity or Overweight With Type 2 Diabetes Mellitus (AURORA-2)

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Ascletis Pharma (China) Co., Limited

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Study ASC30-302 (AURORA-2) is a Phase III, global, multicenter, randomized, double-blind, placebo-controlled study to investigate the long-term efficacy, safety, and tolerability of three maintenance doses of once-daily oral ASC30 compared with placebo in participants with obesity or overweight and T2DM.

Who can join: Review the eligibility criteria below.

Location: AURORA-2 Clinical Site โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (136 Sites)

Showing the first 25 of 136 sites.

  • AURORA-2 Clinical Site โ€” Birmingham, Alabama
  • AURORA-2 Clinical Site โ€” Huntsville, Alabama
  • AURORA-2 Clinical Site โ€” Peoria, Arizona
  • AURORA-2 Clinical Site โ€” Phoenix, Arizona
  • AURORA-2 Clinical Site โ€” Tempe, Arizona
  • AURORA-2 Clinical Site โ€” Tucson, Arizona
  • AURORA-2 Clinical Site โ€” Little Rock, Arkansas
  • AURORA-2 Clinical Site โ€” Banning, California
  • AURORA-2 Clinical Site โ€” Chula Vista, California
  • AURORA-2 Clinical Site โ€” Covina, California
  • AURORA-2 Clinical Site โ€” Gardena, California
  • AURORA-2 Clinical Site โ€” La Mesa, California
  • AURORA-2 Clinical Site โ€” Los Angeles, California
  • AURORA-2 Clinical Site โ€” Sacramento, California
  • AURORA-2 Clinical Site โ€” Tarzana, California
  • AURORA-2 Clinical Site โ€” Tustin, California
  • AURORA-2 Clinical Site โ€” Washington D.C., District of Columbia
  • AURORA-2 Clinical Site โ€” Boca Raton, Florida
  • AURORA-2 Clinical Site โ€” Daytona Beach, Florida
  • AURORA-2 Clinical Site โ€” Jacksonville, Florida
  • AURORA-2 Clinical Site โ€” Leesburg, Florida
  • AURORA-2 Clinical Site โ€” Melbourne, Florida
  • AURORA-2 Clinical Site โ€” South Miami, Florida
  • AURORA-2 Clinical Site โ€” Tampa, Florida
  • AURORA-2 Clinical Site โ€” The Villages, Florida

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Obesity clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—